18956-15-5
Chemical Structure
Pinostrobin chalcone
- CAS No.: 18956-15-5
- Formula:C16H14O4
- Molecular Weight:270.28
IUPAC Name: (E)-1-(2,6-dihydroxy-4-methoxyphenyl)-3-phenylprop-2-en-1-one
InChIKey: CUGDOWNTXKLQMD-BQYQJAHWSA-N
SMILES: O=C(C1=C(C=C(OC)C=C1O)O)/C=C/C2=CC=CC=C2
Biological Activity: Pinostrobin chalcone is a chalcone found in Boesenbergia rotunda and Alpinia mutica. Pinostrobin chalcone exhibits cytotoxicity against various cancer cells. Pinostrobin chalcone is predicted to bind to the JAK active site, forming a hydrogen bond with Asn859 and hydrophobic interactions with aromatic residues. Pinostrobin chalcone can be used in research related to breast cancer, colon cancer, cervical cancer, and epidermoid carcinoma[1][2].
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Pinostrobin chalcone | 99.94% | Pinostrobin chalcone is a chalcone found in Boesenbergia rotunda and Alpinia mutica. Pinostrobin chalcone exhibits cytotoxicity against various cancer cells. Pinostrobin chalcone is predicted to bind to the JAK active site, forming a hydrogen bond with Asn859 and hydrophobic interactions with aromatic residues. Pinostrobin chalcone can be used in research related to breast cancer, colon cancer, cervical cancer, and epidermoid carcinoma. | ||||||||||||||||||||
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Pinostrobin chalcone (Standard) | ≥98% | Pinostrobin chalcone (Standard) is the analytical standard of Pinostrobin chalcone (HY-N3057). This product is intended for research and analytical applications. Pinostrobin chalcone is a chalcone found in Boesenbergia rotunda and Alpinia mutica. Pinostrobin chalcone exhibits cytotoxicity against various cancer cells. Pinostrobin chalcone is predicted to bind to the JAK active site, forming a hydrogen bond with Asn859 and hydrophobic interactions with aromatic residues. Pinostrobin chalcone can be used in research related to breast cancer, colon cancer, cervical cancer, and epidermoid carcinoma. | ||||||||||||||||||||
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References
- [1]. Mohammed I A, et al. Isolation of cardamonin and pinostrobin chalcone from the rhizomes of Boesenbergia rotunda (L.) Mansf. and their cytotoxic effects on H-29 and MDA-MB-231 cancer cell lines[J]. The Natural Products Journal, 2019, 9(4): 341-348.
- [2]. Malek SN, et al. Phytochemical and cytotoxic investigations of Alpinia mutica rhizomes. Molecules (Basel, Switzerland). 2011 Jan 14;16(1):583-9.
