189689-31-4
Chemical Structure
6,7,4'-Trihydroxyflavanone
- CAS No.: 189689-31-4
- Formula:C15H12O5
- Molecular Weight:272.25
IUPAC Name: (S)-6,7-dihydroxy-2-(4-hydroxyphenyl)chroman-4-one
InChIKey: UABMFOBSIHSWFQ-AWEZNQCLSA-N
SMILES: O=C1C2=CC(O)=C(O)C=C2O[C@H](C3=CC=C(C=C3)O)C1
Biological Activity: 6,7,4'-Trihydroxyflavanone is a compound with multiple pharmacological activities, including anti-rheumatic, anti-ischemic, anti-inflammatory, anti-osteoclastogenic and protective T-cells from METH-induced deactivation. 6,7,4'-Trihydroxyflavanone has shown potential protective effects in neurotoxicity studies and can be used to inhibit patients with neurodegenerative diseases caused by METH. 6,7,4'-Trihydroxyflavanone inhibits METH-induced neurotoxicity by upregulating the Nrf2/HO-1 and PI3K/Akt/mTOR signaling pathways. 6,7,4'-Trihydroxyflavanone can also induce Nrf2 nuclear translocation and HO-1 expression, further enhancing its protective effect on neuronal cells[1].
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6,7,4'-Trihydroxyflavanone | 6,7,4'-Trihydroxyflavanone is a compound with multiple pharmacological activities, including anti-rheumatic, anti-ischemic, anti-inflammatory, anti-osteoclastogenic and protective T-cells from METH-induced deactivation. 6,7,4'-Trihydroxyflavanone has shown potential protective effects in neurotoxicity studies and can be used to inhibit patients with neurodegenerative diseases caused by METH. 6,7,4'-Trihydroxyflavanone inhibits METH-induced neurotoxicity by upregulating the Nrf2/HO-1 and PI3K/Akt/mTOR signaling pathways. 6,7,4'-Trihydroxyflavanone can also induce Nrf2 nuclear translocation and HO-1 expression, further enhancing its protective effect on neuronal cells. | |||||||||||||||||||||
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Keywords
