1910124-24-1
1910124-24-1
Chemical Structure
GSK6853
- CAS No.: 1910124-24-1
- Formula:C22H27N5O3
- Molecular Weight:409.48
IUPAC Name: (R)-N-(1,3-dimethyl-6-(2-methylpiperazin-1-yl)-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-5-yl)-2-methoxybenzamide
InChIKey: FQWDVNSBYDXPIO-CQSZACIVSA-N
SMILES: C[C@@H]1CNCCN1C2=C(NC(C3=CC=CC=C3OC)=O)C=C(C(N4C)=C2)N(C)C4=O
Biological Activity: GSK6853, a chemical probe, is a potent and selective inhibitor of the BRPF1 bromodomain. GSK6853 shows excellent BRPF1 potency (pKd = 9.5) and greater than 1600-fold selectivity over all other bromodomains[1].
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GSK6853 | 99.53% | GSK6853, a chemical probe, is a potent and selective inhibitor of the BRPF1 bromodomain. GSK6853 shows excellent BRPF1 potency (pKd = 9.5) and greater than 1600-fold selectivity over all other bromodomains. | ||||||||||||||||||||
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GSK6853 (Standard) | ≥98% | GSK6853 (Standard) is the analytical standard of GSK6853 (HY-100220). This product is intended for research and analytical applications. GSK6853, a chemical probe, is a potent and selective inhibitor of the BRPF1 bromodomain. GSK6853 shows excellent BRPF1 potency (pKd = 9.5) and greater than 1600-fold selectivity over all other bromodomains. | ||||||||||||||||||||
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References
Keywords
