1927930-61-7
Chemical Structure
JMF4073
- CAS No.: 1927930-61-7
- Formula:C18H22FN3O4S
- Molecular Weight:395.45
InChIKey: LBKQSSRUMAUEFE-UHFFFAOYSA-N
SMILES: FC1=CC=C(SN(CC(N2CCN(C(OC(C)(C)C)=O)CC2)=O)C3=O)C3=C1
Biological Activity: JMF4073 is a thymidylate (TMP) and cytidylate (CMP) kinases inhibitor with IC50s of 0.16 μM and 0.17 μM, respectively. JMF4073 eliminates wild-type (WT)-Bcr-Abl-transformed myeloid cells in vitro and in vivo[1].
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JMF4073 | JMF4073 is a thymidylate (TMP) and cytidylate (CMP) kinases inhibitor with IC50s of 0.16 μM and 0.17 μM, respectively. JMF4073 eliminates wild-type (WT)-Bcr-Abl-transformed myeloid cells in vitro and in vivo. | |||||||||||||||||||||
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Keywords