1947-37-1
Chemical Structure
Tetragastrin
Synonym(s): Cholecystokinin tetrapeptide; CCK-4
- CAS No.: 1947-37-1
- Formula:C29H36N6O6S
- Molecular Weight:596.70
IUPAC Name: (S)-4-(((S)-1-amino-1-oxo-3-phenylpropan-2-yl)amino)-3-((S)-2-((S)-2-amino-3-(1H-indol-3-yl)propanamido)-4-(methylthio)butanamido)-4-oxobutanoic acid
InChIKey: RGYLYUZOGHTBRF-BIHRQFPBSA-N
SMILES: NC([C@H](CC1=CC=CC=C1)NC([C@H](CC(O)=O)NC([C@H](CCSC)NC([C@@H](N)CC2=CNC3=CC=CC=C23)=O)=O)=O)=O
Biological Activity: Tetragastrin (Cholecystokinin tetrapeptide; CCK-4) is the C-terminal tetrapeptide of gastrin. Tetragastrin can stimulate gastric secretion[1]. Tetragastrin is a Cholecystokinin (CCK-4) receptor agonist[2]. Gastric mucosal protection[3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Tetragastrin | 99.89% | Tetragastrin (Cholecystokinin tetrapeptide; CCK-4) is the C-terminal tetrapeptide of gastrin. Tetragastrin can stimulate gastric secretion. Tetragastrin is a Cholecystokinin (CCK-4) receptor agonist. Gastric mucosal protection. | ||||||||||||||||||||
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Similarity Score 0.82
HY-124192Amogastrin -
Similarity Score 0.80
HY-A0261Pentagastrin -
Similarity Score 0.76
HY-P3540Y-{d-Trp}-GFM-NH2 -
Similarity Score 0.75
HY-P11540CCKBR agonist-1 -
Similarity Score 0.74
HY-P2627CCK (27-33) -
Similarity Score 0.73
HY-P4709(Trp7,β-Ala8)-Neurokinin A (4-10) -
Similarity Score 0.73
HY-P2165N-acetyl CCK-(26-30) amide -
Similarity Score 0.72
HY-P2678CCK (26-31) non-sulfated -
Similarity Score 0.72
HY-P2055A-57696 -
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References
- [1]. M Tatsuta, et al. Effect of 6-hydroxydopamine on gastric carcinogenesis and tetragastrin inhibition of gastric carcinogenesis induced by N-methyl-N'-nitro-N-nitrosoguanidine in Wistar rats. Cancer Res. 1989 Aug 1;49(15):4199-203. [Content Brief]
- [2]. Nathalie Lara, et al. Pulmonary and systemic nitric oxide measurements during CCK-5-induced panic attacks. Neuropsychopharmacology. 2003 Oct;28(10):1840-5. [Content Brief]
- [3]. Y Komuro,et al. Effects of tetragastrin on mucus glycoprotein in rat gastric mucosal protection. Gastroenterol Jpn. 1992 Oct;27(5):597-603. [Content Brief]
