1948232-63-0
1948232-63-0
Chemical Structure
Filapixant
Synonym(s): BAY 1902607
- CAS. Nr.: 1948232-63-0
- Formula:C24H26F3N5O3S
- Molecular Weight:521.56
IUPAC Name: 3-(((R)-4-methylmorpholin-2-yl)methoxy)-5-(5-methylthiazol-2-yl)-N-((R)-1-(2-(trifluoromethyl)pyrimidin-5-yl)ethyl)benzamide
InChIKey: MROBUJILSMBILX-FOIQADDNSA-N
SMILES: O=C(N[C@@H](C1=CN=C(C(F)(F)F)N=C1)C)C2=CC(C3=NC=C(C)S3)=CC(OC[C@H]4CN(C)CCO4)=C2
Biological Activity: Filapixant (BAY 1902607) is an orally active and selective P2X3 receptor antagonist. Filapixant is applicable to the research of refractory chronic cough[1].
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Filapixant | 99.10% | Filapixant (BAY 1902607) is an orally active and selective P2X3 receptor antagonist. Filapixant is applicable to the research of refractory chronic cough. | ||||||||||||||||||||
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Filapixant (Standard) | ≥98% | Filapixant (Standard) is the analytical standard of Filapixant (HY-109173). This product is intended for research and analytical applications. Filapixant is a purinoreceptor antagonist extracted from patent WO2016091776A1, example 348. Filapixant is the active reference substance of Eliapixant. | ||||||||||||||||||||
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References
- [1]. Francke K, et al. Investigation of the Relevance of CYP3A4 Inhibition on the Pharmacokinetics of the Novel P2X3 Antagonist Filapixant: Results of In Vitro Explorations and a Fixed-Sequence Clinical Trial with Itraconazole in Healthy Volunteers. Int J Mol Sci. 2025;26(20):10177. Published 2025 Oct 20. [Content Brief]
