1957235-73-2
1957235-73-2
Chemical Structure
Thalidomide-O-CH2-CO-NH-C2-PEG2-NH-Boc
- CAS No.: 1957235-73-2
- Formula:C26H34N4O10
- Molecular Weight:562.57
SMILES: O=C(OC(C)(C)C)NCCOCCOCCNC(COC1=CC=CC(C(N2C(CC3)C(NC3=O)=O)=O)=C1C2=O)=O
Biological Activity: Thalidomide-O-COOH-NH2-C2-PEG2-NH-Boc is a conjugate of E3 ligase ligand and linker, which contains Thalidomide-based CEREBLON ligand and PEG inker. Thalidomide-O-COOH-NH2-C2-PEG2-NH-Boc can be used to synthesize PROTAC degrader JB300 (HY-137341)[1].
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Thalidomide-O-CH2-CO-NH-C2-PEG2-NH-Boc | Thalidomide-O-COOH-NH2-C2-PEG2-NH-Boc is a conjugate of E3 ligase ligand and linker, which contains Thalidomide-based CEREBLON ligand and PEG inker. Thalidomide-O-COOH-NH2-C2-PEG2-NH-Boc can be used to synthesize PROTAC degrader JB300 (HY-137341). | |||||||||||||||||||||
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References
