19622-05-0
19622-05-0
Chemical Structure
Pellotine
- CAS No.: 19622-05-0
- Formula:C13H19NO3
- Molecular Weight:237.29
InChIKey: NKHMWHLJHODBEP-UHFFFAOYSA-N
SMILES: COC1=C(OC)C(O)=C(C(C)N(C)CC2)C2=C1
Biological Activity: Pellotine is an alkaloid that can be isolated from Lophophora. Pellotine is the inverse agonist for 5-HT7 receptor with an EC50 of 291 nM. Pellotine exhibits good affinity to 5-HT1DR and 5-HT6R with Ki of 117 nM and 170 nM. Pellotine reduces intracellular cAMP levels, thereby reducing neuronal excitability and neurotransmitter release[1].
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Pellotine | Pellotine is an alkaloid that can be isolated from Lophophora. Pellotine is the inverse agonist for 5-HT7 receptor with an EC50 of 291 nM. Pellotine exhibits good affinity to 5-HT1DR and 5-HT6R with Ki of 117 nM and 170 nM. Pellotine reduces intracellular cAMP levels, thereby reducing neuronal excitability and neurotransmitter release. | |||||||||||||||||||||
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