1962931-71-0
1962931-71-0
Chemical Structure
JNJ-DGAT2-A
- CAS No.: 1962931-71-0
- Formula:C24H16BrFN4O2S
- Molecular Weight:523.38
IUPAC Name: (Z)-3-bromo-4-(2-fluoro-4-((4-oxo-2-((2-(pyridin-2-yl)ethyl)amino)thiazol-5(4H)-ylidene)methyl)phenoxy)benzonitrile
InChIKey: ZFRHAMOJHTZHLT-XKZIYDEJSA-N
SMILES: BrC1=C(C=CC(C#N)=C1)OC2=C(C=C(C=C2)/C=C3SC(NCCC4=CC=CC=N4)=NC\3=O)F
Biological Activity: JNJ-DGAT2-A is a selective diacylglycerol acyltransferase 2 (DGAT2) inhibitor with an IC50 value of 0.14 μM in human DGAT2-expressing Sf9 insect cell membranes. JNJ-DGAT2-A can be used for the research of triglyceride (TG) synthesis[1].
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JNJ-DGAT2-A | 98.26% | JNJ-DGAT2-A is a selective diacylglycerol acyltransferase 2 (DGAT2) inhibitor with an IC50 value of 0.14 μM in human DGAT2-expressing Sf9 insect cell membranes. JNJ-DGAT2-A can be used for the research of triglyceride (TG) synthesis. | ||||||||||||||||||||
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References
Keywords
