1976050-09-5
1976050-09-5
Chemical Structure
Valiglurax
Synonym(s): VU0652957; VU2957
- CAS No.: 1976050-09-5
- Formula:C16H10F3N5
- Molecular Weight:329.28
IUPAC Name: N-(1H-pyrazolo[3,4-b]pyridin-3-yl)-1-(trifluoromethyl)isoquinolin-6-amine
InChIKey: RUEXKBWCUUFJMY-UHFFFAOYSA-N
SMILES: FC(C1=NC=CC2=C1C=CC(NC3=NNC4=NC=CC=C43)=C2)(F)F
Biological Activity: Valiglurax (VU0652957) is a potent, orally active and selective mGlu4 positive allosteric modulator with EC50 values of 64.6 nM and 197 nM for hmGlu4/Gqi5 and rmGlu4 GIRK, respectively. Valiglurax is a central nervous system (CNS) penetrant. Valiglurax can be used in research of Parkinson's disease[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Valiglurax | 99.22% | Valiglurax (VU0652957) is a potent, orally active and selective mGlu4 positive allosteric modulator with EC50 values of 64.6 nM and 197 nM for hmGlu4/Gqi5 and rmGlu4 GIRK, respectively. Valiglurax is a central nervous system (CNS) penetrant. Valiglurax can be used in research of Parkinson's disease. | ||||||||||||||||||||
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