1990479-14-5
1990479-14-5
Chemical Structure
CRK12-IN-1
- CAS No.: 1990479-14-5
- Formula:C20H26F2N4O3S2
- Molecular Weight:472.57
IUPAC Name: N-((1r,4r)-4-((4-amino-5-(2,6-difluorobenzoyl)thiazol-2-yl)amino)cyclohexyl)-2-methylpropane-1-sulfonamide
InChIKey: DZBBFJPWMFEESI-JOCQHMNTSA-N
SMILES: O=S(N[C@@H]1CC[C@@H](NC2=NC(N)=C(C(C3=C(F)C=CC=C3F)=O)S2)CC1)(CC(C)C)=O
Biological Activity: CRK12-IN-1 is a potent CRK12 inhibitor. CRK12-IN-1 is extremely potent against T.b. brucei and rapidly cytocidal, as well as equally potent against T. congolense and T. vivax (EC50 of 1.3 and 18 nM, respectively)[1].
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CRK12-IN-1 | CRK12-IN-1 is a potent CRK12 inhibitor. CRK12-IN-1 is extremely potent against T.b. brucei and rapidly cytocidal, as well as equally potent against T. congolense and T. vivax (EC50 of 1.3 and 18 nM, respectively). | |||||||||||||||||||||
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