2001072-35-9
2001072-35-9
Chemical Structure
DC_YM21
- CAS No.: 2001072-35-9
- Formula:C26H33ClN2
- Molecular Weight:409.01
IUPAC Name: 4-(4-(4-chlorophenyl)-3,6-dihydropyridin-1(2H)-yl)-2-cyclopentyl-2-phenylbutan-1-amine
InChIKey: ROBJDFLYWHJESD-UHFFFAOYSA-N
SMILES: NCC(C1CCCC1)(CCN2CC=C(CC2)C3=CC=C(C=C3)Cl)C4=CC=CC=C4
Biological Activity: DC_YM21 is an inhibitor of menin-MLL interaction with potent and selective proliferation blocking activity. DC_YM21 can induce cell cycle arrest and differentiation of leukemia cells carrying MLL translocation. DC_YM21 shows potential application value in inhibiting MLL leukemia[1].
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DC_YM21 | DC_YM21 is an inhibitor of menin-MLL interaction with potent and selective proliferation blocking activity. DC_YM21 can induce cell cycle arrest and differentiation of leukemia cells carrying MLL translocation. DC_YM21 shows potential application value in inhibiting MLL leukemia. | |||||||||||||||||||||
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