200716-66-1
200716-66-1
Chemical Structure
1,3-PBIT dihydrobromide
- CAS No.: 200716-66-1
- Formula:C12H20Br2N4S2
- Molecular Weight:444.25
IUPAC Name: 1,3-phenylenebis(ethane-2,1-diyl) dicarbamimidothioate dihydrobromide
InChIKey: WCXGFTJSDASEPR-UHFFFAOYSA-N
SMILES: NC(SCCC1=CC(CCSC(N)=N)=CC=C1)=N.Br.Br
Biological Activity: 1,3-PBIT is a potent inhibitor of iNOS with a Ki of 47 nM compared to Ki values for eNOS and nNOS are 9 and 0.25 μM, respectively, for the purified human enzymes. Its inhibition in whole cells is greatly diminished, presumably to poor membrane permeability.
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1,3-PBIT dihydrobromide | 98% | 1,3-PBIT is a potent inhibitor of iNOS with a Ki of 47 nM compared to Ki values for eNOS and nNOS are 9 and 0.25 μM, respectively, for the purified human enzymes. Its inhibition in whole cells is greatly diminished, presumably to poor membrane permeability. | ||||||||||||||||||||
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Keywords
