2010154-82-0
Chemical Structure
ABD-1970
- CAS No.: 2010154-82-0
- Formula:C21H24ClF6N3O3
- Molecular Weight:515.88
IUPAC Name: 1,1,1,3,3,3-hexafluoropropan-2-yl 4-(2-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-4-chlorobenzyl)piperazine-1-carboxylate
InChIKey: CXSFVTMRWPSLGO-UHFFFAOYSA-N
SMILES: O=C(N1CCN(CC2=CC=C(Cl)C=C2N3CC(O4)CCC4C3)CC1)OC(C(F)(F)F)C(F)(F)F
Biological Activity: ABD-1970 is a selective monoacylglycerol lipase (MAGL) inhibitor with IC50s of 15 nM and 29 nM for human and mouse MAGL, respectively. ABD-1970 shows selectivity for MGLL over other members of the serine hydrolase class. ABD-1970 has the potential for the study of neurological disorders[1].
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ABD-1970 | ABD-1970 is a selective monoacylglycerol lipase (MAGL) inhibitor with IC50s of 15 nM and 29 nM for human and mouse MAGL, respectively. ABD-1970 shows selectivity for MGLL over other members of the serine hydrolase class. ABD-1970 has the potential for the study of neurological disorders. | |||||||||||||||||||||
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Keywords
