2030410-25-2

Glasdegib maleate Chemical Structure
2030410-25-2

Chemical Structure

Glasdegib maleate

Synonym(s): PF-04449913 maleate

  • CAS No.: 2030410-25-2
  • Formula:C25H26N6O5
  • Molecular Weight:490.51

IUPAC Name: 1-((2R,4R)-2-(1H-benzo[d]imidazol-2-yl)-1-methylpiperidin-4-yl)-3-(4-cyanophenyl)urea maleate

InChIKey: VJCVKWFBWAVYOC-UIXXXISESA-N

SMILES: O=C(NC1=CC=C(C#N)C=C1)N[C@H]2C[C@H](C3=NC4=CC=CC=C4N3)N(C)CC2.OC(/C=C\C(O)=O)=O

Biological Activity: Glasdegib maleate (PF-04449913 maleate) is a potent and orally bioavailable smoothened inhibitor. Glasdegib maleate binds to human SMO (amino acids 181-787) with IC50value of 4 nM[1].

Cat. No. Product Name Purity Description Pricing
HY-16391A 		Glasdegib maleate Glasdegib maleate (PF-04449913 maleate) is a potent and orally bioavailable smoothened inhibitor. Glasdegib maleate binds to human SMO (amino acids 181-787) with IC50value of 4 nM.
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