2048491-06-9
2048491-06-9
Chemical Structure
FPT
- CAS No.: 2048491-06-9
- Formula:C18H20FN
- Molecular Weight:269.36
InChIKey: PCFGMPNKAUVMPL-AWEZNQCLSA-N
SMILES: FC1=C(C=CC=C1)C2=C3C(C[C@H](CC3)N(C)C)=CC=C2
Biological Activity: FPT, a 2-Aminotetralin, is an efficacious partial agonist at 5-HT1AR, a full agonist at 5-HT1BR and 5-HT1DR with EC50s of 39.3 nM, 1.2 nM, 0.5 nM, respectively. FPT is a weak agonist at 5-HT7R. FPT shows in vivo efficacy as an antiepileptic in Fmr1 knockout mice and has anxiolytic-like and prosocial effects in Fmr1 knockout mice and other mouse models[1].
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FPT | 98.06% | FPT, a 2-Aminotetralin, is an efficacious partial agonist at 5-HT1AR, a full agonist at 5-HT1BR and 5-HT1DR with EC50s of 39.3 nM, 1.2 nM, 0.5 nM, respectively. FPT is a weak agonist at 5-HT7R. FPT shows in vivo efficacy as an antiepileptic in Fmr1 knockout mice and has anxiolytic-like and prosocial effects in Fmr1 knockout mice and other mouse models. | ||||||||||||||||||||
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