20535-76-6
Chemical Structure
p18SMI-21
- CAS No.: 20535-76-6
- Formula:C10H14N2O4S
- Molecular Weight:258.29
IUPAC Name: N-(4-(N-(2-hydroxyethyl)sulfamoyl)phenyl)acetamide
InChIKey: VUYBWFBHHFQGDM-UHFFFAOYSA-N
SMILES: CC(NC1=CC=C(C=C1)S(=O)(NCCO)=O)=O
Biological Activity: p18SMI-21 is a novel INK4C inhibitor that specifically blocks the biological activity of p18 protein. p18SMI-21 exerts its anti-gastric acid effect through direct contact, and the intensity of this effect varies with the dose. p18SMI-21 can significantly reduce the proteolytic activity of pepsin under certain conditions. The inhibitory effect of p18SMI-21 is best achieved in direct contact with the substrate. If it contacts the substrate first, the inhibitory effect will be lost[1].
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p18SMI-21 | p18SMI-21 is a novel INK4C inhibitor that specifically blocks the biological activity of p18 protein. p18SMI-21 exerts its anti-gastric acid effect through direct contact, and the intensity of this effect varies with the dose. p18SMI-21 can significantly reduce the proteolytic activity of pepsin under certain conditions. The inhibitory effect of p18SMI-21 is best achieved in direct contact with the substrate. If it contacts the substrate first, the inhibitory effect will be lost. | |||||||||||||||||||||
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