2055496-11-0
2055496-11-0
Chemical Structure
Cedirogant
Synonym(s): ABBV-157
- CAS No.: 2055496-11-0
- Formula:C24H20Cl3F3N2O3
- Molecular Weight:547.78
IUPAC Name: 2-(1-(2,4-dichloro-3-((7-chloro-5-(trifluoromethyl)-1H-indol-1-yl)methyl)benzoyl)piperidin-4-yl)acetic acid
InChIKey: MNEOHCYSHVKLIC-UHFFFAOYSA-N
SMILES: O=C(CC1CCN(CC1)C(C2=CC=C(C(CN3C=CC4=C3C(Cl)=CC(C(F)(F)F)=C4)=C2Cl)Cl)=O)O
Biological Activity: Cedirogant (ABBV-157) is an orally active RORγt inverse agonist. Cedirogant can be used for psoriasis research[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Cedirogant | 98.66% | Cedirogant (ABBV-157) is an orally active RORγt inverse agonist. Cedirogant can be used for psoriasis research. | ||||||||||||||||||||
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References
- [1]. Elena Campione, et al. Experimental Pharmacological Management of Psoriasis. J Exp Pharmacol. 2021 Jul 26;13:725-737. [Content Brief]
- [2]. Christian Gege. Retinoic acid-related orphan receptor gamma t (RORγt) inverse agonists/antagonists for the treatment of inflammatory diseases - where are we presently? Expert Opin Drug Discov. 2021 Jul 7;1-19. [Content Brief]
