2056014-40-3
Chemical Structure
BLM-IN-1
- CAS No.: 2056014-40-3
- Formula:C28H35FN4O
- Molecular Weight:462.60
IUPAC Name: (E)-6-((3-(diethylamino)propyl)amino)-7-fluoro-3-(4-isopropylbenzylidene)-2,3-dihydropyrrolo[2,1-b]quinazolin-9(1H)-one
InChIKey: GZSNGNPLURZQGM-CJLVFECKSA-N
SMILES: CCN(CC)CCCNC1=CC(N=C(/C(CC2)=C/C3=CC=C(C(C)C)C=C3)N2C4=O)=C4C=C1F
Biological Activity: BLM-IN-1 is an effective bloom syndrome protein (BLM) inhibitor. BLM-IN-1 has a high binding affinity with a KD valueof 1.81 μM. BLM-IN-1 has good inhibitory effect for BLM with an IC50 value of 0.95 μM. BLM-IN-1 can induce cell apoptosis. BLM-IN-1can be used for the research of DNA damage and cancer[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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BLM-IN-1 | 98.04% | BLM-IN-1 is an effective bloom syndrome protein (BLM) inhibitor. BLM-IN-1 has a high binding affinity with a KD valueof 1.81 μM. BLM-IN-1 has good inhibitory effect for BLM with an IC50 value of 0.95 μM. BLM-IN-1 can induce cell apoptosis. BLM-IN-1can be used for the research of DNA damage and cancer. | ||||||||||||||||||||
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Keywords
