1. Apoptosis
  2. Apoptosis
  3. BLM-IN-1

BLM-IN-1 

Cat. No.: HY-111756
Handling Instructions

BLM-IN-1 (compound 29) is an effective Bloom syndrome protein (BLM) inhibitor, with a strong BLM binding KD of 1.81 μM and an IC50 of 0.95 μM for BLM. Induces DNA damage response, as well as apoptosis and proliferation arrest in cancer cells.

For research use only. We do not sell to patients.

BLM-IN-1 Chemical Structure

BLM-IN-1 Chemical Structure

CAS No. : 2056014-40-3

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Description

BLM-IN-1 (compound 29) is an effective Bloom syndrome protein (BLM) inhibitor, with a strong BLM binding KD of 1.81 μM and an IC50 of 0.95 μM for BLM. Induces DNA damage response, as well as apoptosis and proliferation arrest in cancer cells[1].

IC50 & Target

IC50: 1.95 μM (BLM)[1].

Molecular Weight

462.60

Formula

C₂₈H₃₅FN₄O

CAS No.

2056014-40-3

SMILES

CCN(CC)CCCNC1=CC(N=C(/C(CC2)=C/C3=CC=C(C(C)C)C=C3)N2C4=O)=C4C=C1F

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

BLM-IN-1ApoptosisInhibitorinhibitorinhibit

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BLM-IN-1
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