2057420-29-6

BRD9185 Chemical Structure
2057420-29-6

Chemical Structure

BRD9185

  • CAS No.: 2057420-29-6
  • Formula:C23H21F6N3O2
  • Molecular Weight:485.42

IUPAC Name: (2S,3S,4S)-3-(3',4'-bis(trifluoromethyl)-[1,1'-biphenyl]-4-yl)-2-cyano-4-(hydroxymethyl)-N-propylazetidine-1-carboxamide

InChIKey: FYPZBZFXJUJJRA-AQNXPRMDSA-N

SMILES: O=C(N1[C@@H]([C@H]([C@H]1C#N)C2=CC=C(C3=CC=C(C(C(F)(F)F)=C3)C(F)(F)F)C=C2)CO)NCCC

Biological Activity: BRD9185 is a Dihydroorotate dehydrogenase (DHODH) inhibitor, with an EC50 of 16 nM against multidrug-resistant blood-stage parasites in vitro and is curative after just three doses in a P. berghei mouse model[1].

Cat. No. Product Name Purity Description Pricing
HY-120924 		BRD9185 BRD9185 is a Dihydroorotate dehydrogenase (DHODH) inhibitor, with an EC50 of 16 nM against multidrug-resistant blood-stage parasites in vitro and is curative after just three doses in a P. berghei mouse model.
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