2079892-79-6
2079892-79-6
Chemical Structure
RORγt Inverse agonist 8
- CAS No.: 2079892-79-6
- Formula:C26H33N7O2
- Molecular Weight:475.59
IUPAC Name: (S)-N-(8-((4-(cyclopentanecarbonyl)-3-methylpiperazin-1-yl)methyl)-7-methylimidazo[1,2-a]pyridin-6-yl)-2-methylpyrimidine-5-carboxamide
InChIKey: GMRCLEMCHGYDSY-KRWDZBQOSA-N
SMILES: O=C(C1=CN=C(C)N=C1)NC2=CN3C(C(CN4C[C@H](C)N(C(C5CCCC5)=O)CC4)=C2C)=NC=C3
Biological Activity: RORγt Inverse agonist 8 is a potent, selective, orally bioavailable RORγt inverse agonist, with an IC50 of 19 nM for human RORγt-LBD[1].
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RORγt Inverse agonist 8 | RORγt Inverse agonist 8 is a potent, selective, orally bioavailable RORγt inverse agonist, with an IC50 of 19 nM for human RORγt-LBD. | |||||||||||||||||||||
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