208116-26-1
Chemical Structure
KAFDITYVRLKF
- CAS No.: 208116-26-1
- Formula:C73H113N17O17
- Molecular Weight:1500.81
IUPAC Name: (2S,5S,8S,11S,14S,17S,20S,23S,26S)-5-(4-aminobutyl)-2-benzyl-23-((S)-sec-butyl)-26-((S)-2-((S)-2-((S)-2,6-diaminohexanamido)propanamido)-3-phenylpropanamido)-11-(3-guanidinopropyl)-17-(4-hydroxybenzyl)-20-((R)-1-hydroxyethyl)-8-isobutyl-14-isopropyl-4,7,10,13,16,19,22,25-octaoxo-3,6,9,12,15,18,21,24-octaazaoctacosanedioic acid
InChIKey: KBCXTQVDKPAYQJ-KHTXFUALSA-N
SMILES: [C@H](CC1=CC=C(O)C=C1)(C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC2=CC=CC=C2)C(O)=O)=O)CCCCN)=O)CC(C)C)=O)CCCNC(=N)N)=O)C(C)C)=O)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC3=CC=CC=C3)NC([C@@H](NC([C@H](CCCCN)N)=O)C)=O)=O)CC(O)=O)=O)[C@H](CC)C)=O)[C@@H](C)O)=O
Biological Activity: KAFDITYVRLKF is a selective, competitive integrin αvβ3 binder. KAFDITYVRLKF induces the production of MMP-9. KAFDITYVRLKF blocks monocyte migration, promotes melanoma cell migration, protects neurons, and improves motor and cognitive functions. KAFDITYVRLKF can be used in research related to melanoma and Parkinson's disease[1][2].
| Cat. No. | 상품명 | Purity | 제품 설명 | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
KAFDITYVRLKF | KAFDITYVRLKF is a selective, competitive integrin αvβ3 binder. KAFDITYVRLKF induces the production of MMP-9. KAFDITYVRLKF blocks monocyte migration, promotes melanoma cell migration, protects neurons, and improves motor and cognitive functions. KAFDITYVRLKF can be used in research related to melanoma and Parkinson's disease. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
- [1]. Kuratomi Y, et al. Laminin gamma 1 chain peptide, C-16 (KAFDITYVRLKF), promotes migration, MMP-9 secretion, and pulmonary metastasis of B16-F10 mouse melanoma cells. Br J Cancer. 2002;86(7):1169-1173. [Content Brief]
- [2]. Cai HY, et al. Adjusting vascular permeability, leukocyte infiltration, and microglial cell activation to rescue dopaminergic neurons in rodent models of Parkinson's disease. NPJ Parkinsons Dis. 2021;7(1):91. Published 2021 Oct 8. [Content Brief]
