2086301-47-3
Chemical Structure
(S,R,S)-AHPC-Boc-trans-3-aminocyclobutanol-Pip-CH2COOH
Synonym(s): VH032-Boc-trans-3-aminocyclobutanol-Pip-CH2COOH
- CAS No.: 2086301-47-3
- Formula:C39H58N6O7S
- Molecular Weight:754.98
IUPAC Name: tert-butyl ((1S,3r)-3-((1-(2-(((S)-1-((2S,4R)-4-hydroxy-2-(((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)carbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)amino)-2-oxoethyl)piperidin-4-yl)oxy)cyclobutyl)carbamate
InChIKey: MBBHQLTUHKETEL-GHNUVCSISA-N
SMILES: O=C(CN1CCC(O[C@H]2C[C@H](NC(OC(C)(C)C)=O)C2)CC1)N[C@H](C(N([C@H](C(N[C@@H](C)C3=CC=C(C=C3)C4=C(C)N=CS4)=O)C5)C[C@@H]5O)=O)C(C)(C)C
Biological Activity: (S,R,S)-AHPC-Boc-trans-3-aminocyclobutanol-Pip-CH2COOH (VH032-Boc-trans-3-aminocyclobutanol-Pip-CH2COOH) is a E3 ligase ligand-linker conjugate that contains on one end a VHL ligand. (S,R,S)-AHPC-Boc-trans-3-aminocyclobutanol-Pip-CH2COOH is used in PROTAC technology[1].
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(S,R,S)-AHPC-Boc-trans-3-aminocyclobutanol-Pip-CH2COOH | 98.57% | (S,R,S)-AHPC-Boc-trans-3-aminocyclobutanol-Pip-CH2COOH (VH032-Boc-trans-3-aminocyclobutanol-Pip-CH2COOH) is a E3 ligase ligand-linker conjugate that contains on one end a VHL ligand. (S,R,S)-AHPC-Boc-trans-3-aminocyclobutanol-Pip-CH2COOH is used in PROTAC technology. | ||||||||||||||||||||
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