2095883-62-6
2095883-62-6
Chemical Structure
DPPY
- CAS No.: 2095883-62-6
- Formula:C25H26ClN7O3
- Molecular Weight:507.97
IUPAC Name: N-(3-((5-chloro-2-((4-(2-morpholinoacetamido)phenyl)amino)pyrimidin-4-yl)amino)phenyl)acrylamide
InChIKey: YULLFCKYQFTWEM-UHFFFAOYSA-N
SMILES: C=CC(NC1=CC(NC2=NC(NC3=CC=C(C=C3)NC(CN4CCOCC4)=O)=NC=C2Cl)=CC=C1)=O
Biological Activity: DPPY (compound 6) is a potent PTK inhibitor with IC50 values of <10, <10, <10 nM for EGFR, BTK, JAK3, respectively. DPPY shows anti-proliferative activity against B-cell lymphoma cells. DPPY has the potential for the research of idiopathic pulmonary fibrosis (IPF)[1].
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DPPY | DPPY (compound 6) is a potent PTK inhibitor with IC50 values of <10, <10, <10 nM for EGFR, BTK, JAK3, respectively. DPPY shows anti-proliferative activity against B-cell lymphoma cells. DPPY has the potential for the research of idiopathic pulmonary fibrosis (IPF). | |||||||||||||||||||||
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References
Keywords
