2097148-94-0
2097148-94-0
Chemical Structure
LXQ46
- CAS No.: 2097148-94-0
- Formula:C23H17Br2NO5
- Molecular Weight:547.19
InChIKey: MOHJRHPKFDUKBW-UHFFFAOYSA-N
SMILES: BrC1=C(O)C(O)=CC(C2=NC=C(C3=CC=C(OC4=CC=C(C=C4)OCC)C=C3)O2)=C1Br
Biological Activity: LXQ46 is an orally active inhibitor for protein tyrosine phosphatase 1B (PTP1B), with an IC50 of 0.190 μM. LXQ46 enhances insulin and leptin signaling pathways in insulin-resistant C2C12. LXQ46 ameliorates type 2 diabetes and increases insulin tolerance in mouse models[1].
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LXQ46 | 99.14% | LXQ46 is an orally active inhibitor for protein tyrosine phosphatase 1B (PTP1B), with an IC50 of 0.190 μM. LXQ46 enhances insulin and leptin signaling pathways in insulin-resistant C2C12. LXQ46 ameliorates type 2 diabetes and increases insulin tolerance in mouse models. | ||||||||||||||||||||
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References
Keywords
