2098466-94-3
2098466-94-3
Chemical Structure
TyK2-IN-2
- CAS No.: 2098466-94-3
- Formula:C16H18N6O
- Molecular Weight:310.35
IUPAC Name: 6-((3,5-dimethylphenyl)amino)-8-(methylamino)imidazo[1,2-b]pyridazine-3-carboxamide
InChIKey: SNVFFECYFQEWTL-UHFFFAOYSA-N
SMILES: CNC1=CC(NC2=CC(C)=CC(C)=C2)=NN3C1=NC=C3C(N)=O
Biological Activity: TyK2-IN-2 (Compoud 18) is a potent and selective TYK2 inhibitor with IC50s of 7 nM, 0.1 μM and 0.05 μM for TYK2 JH2, IL-23 and IFNα, respectively. TyK2-IN-2 also inhibits phosphodiesterase 4 (PDE4) with an IC50 of 62 nM. TyK2-IN-2 can be used for the research of inflammatory and autoimmune diseases[1].
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TyK2-IN-2 | 99.05% | TyK2-IN-2 (Compoud 18) is a potent and selective TYK2 inhibitor with IC50s of 7 nM, 0.1 μM and 0.05 μM for TYK2 JH2, IL-23 and IFNα, respectively. TyK2-IN-2 also inhibits phosphodiesterase 4 (PDE4) with an IC50 of 62 nM. TyK2-IN-2 can be used for the research of inflammatory and autoimmune diseases. | ||||||||||||||||||||
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TyK2-IN-2 (Standard) | ≥98% | TyK2-IN-2 (Standard) is the analytical standard of TyK2-IN-2 (HY-101762). This product is intended for research and analytical applications. TyK2-IN-2 (Compoud 18) is a potent and selective TYK2 inhibitor with IC50s of 7 nM, 0.1 μM and 0.05 μM for TYK2 JH2, IL-23 and IFNα, respectively. TyK2-IN-2 also inhibits phosphodiesterase 4 (PDE4) with an IC50 of 62 nM. TyK2-IN-2 can be used for the research of inflammatory and autoimmune diseases. | ||||||||||||||||||||
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