2098487-52-4

Thalidomide-O-PEG2-propargyl Chemical Structure
2098487-52-4

Chemical Structure

Thalidomide-O-PEG2-propargyl

Synonym(s): E3 ligase Ligand-Linker Conjugates 32

  • CAS. Nr.: 2098487-52-4
  • Formula:C20H20N2O7
  • Molecular Weight:400.38

IUPAC Name: 2-(2,6-dioxopiperidin-3-yl)-4-(2-(2-(prop-2-yn-1-yloxy)ethoxy)ethoxy)isoindoline-1,3-dione

InChIKey: XJWGDRINRIEEJD-UHFFFAOYSA-N

SMILES: O=C1N(C(CC2)C(NC2=O)=O)C(C3=C1C=CC=C3OCCOCCOCC#C)=O

Biological Activity: Thalidomide-O-PEG2-propargyl (E3 ligase Ligand-Linker Conjugates 32) is an E3 ligase ligand-linker conjugate. Thalidomide-O-PEG2-propargyl is also a click chemistry reagent containing an alkyne group, which can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAC) with molecules bearing an azide group[1].

Art. -Nr. Produktname Reinheit Beschreibung Pricing
HY-126458
Thalidomide-O-PEG2-propargyl 97.80% Thalidomide-O-PEG2-propargyl (E3 ligase Ligand-Linker Conjugates 32) is an E3 ligase ligand-linker conjugate. Thalidomide-O-PEG2-propargyl is also a click chemistry reagent containing an alkyne group, which can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAC) with molecules bearing an azide group.
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This compound is listed in the SVHC (Substances of Very High Concern) candidate list of ECHA (European Chemicals Agency).

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References