2101821-86-5
Chemical Structure
LRRK2-IN-17
- CAS No.: 2101821-86-5
- Formula:C18H18N8
- Molecular Weight:346.39
InChIKey: ZQSBNCTWGKRISE-AWEZNQCLSA-N
SMILES: CN1C=C(NC2=NC(N[C@@H]3C4=C(C=CC=C4)CC3)=C5C=CNC5=N2)N=N1
Biological Activity: LRRK2-IN-17 (Compound 6) is an orally active LRRK2 inhibitor (IC50: 3.5 and 3.3 nM for WT and G2019S, respectively). LRRK2-IN-17 inhibits RET kinase (IC50: 59 nM). LRRK2-IN-17 can be used in cancer and Parkinson's disease (PD) research[1].
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LRRK2-IN-17 | LRRK2-IN-17 (Compound 6) is an orally active LRRK2 inhibitor (IC50: 3.5 and 3.3 nM for WT and G2019S, respectively). LRRK2-IN-17 inhibits RET kinase (IC50: 59 nM). LRRK2-IN-17 can be used in cancer and Parkinson's disease (PD) research. | |||||||||||||||||||||
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Keywords