2101821-86-5

LRRK2-IN-17 Chemical Structure
2101821-86-5

Chemical Structure

LRRK2-IN-17

  • CAS No.: 2101821-86-5
  • Formula:C18H18N8
  • Molecular Weight:346.39

InChIKey: ZQSBNCTWGKRISE-AWEZNQCLSA-N

SMILES: CN1C=C(NC2=NC(N[C@@H]3C4=C(C=CC=C4)CC3)=C5C=CNC5=N2)N=N1

Biological Activity: LRRK2-IN-17 (Compound 6) is an orally active LRRK2 inhibitor (IC50: 3.5 and 3.3 nM for WT and G2019S, respectively). LRRK2-IN-17 inhibits RET kinase (IC50: 59 nM). LRRK2-IN-17 can be used in cancer and Parkinson's disease (PD) research[1].

Cat. No. Product Name Purity Description Pricing
HY-172952
LRRK2-IN-17 LRRK2-IN-17 (Compound 6) is an orally active LRRK2 inhibitor (IC50: 3.5 and 3.3 nM for WT and G2019S, respectively). LRRK2-IN-17 inhibits RET kinase (IC50: 59 nM). LRRK2-IN-17 can be used in cancer and Parkinson's disease (PD) research.
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