2102681-49-0
2102681-49-0
Chemical Structure
SHMT-IN-2
- CAS No.: 2102681-49-0
- Formula:C22H24F3N5O
- Molecular Weight:431.45
IUPAC Name: 6-amino-4-isopropyl-3-methyl-4-(3-(pyrrolidin-1-yl)-5-(trifluoromethyl)phenyl)-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile
InChIKey: NOKJZHRLDAOFCV-UHFFFAOYSA-N
SMILES: NC1=C(C#N)C(C2=CC(N3CCCC3)=CC(C(F)(F)F)=C2)(C(C)C)C(C(C)=NN4)=C4O1
Biological Activity: SHMT-IN-2 is a stereo specific inhibitor of human SHMT1/2 with IC50 values of 13 nM and 66 nM for SHMT1 and SHMT2, respectively. SHMT-IN-2 can block the growth of many human cancer cells, and has sensitivity for B-cell lymphomas[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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SHMT-IN-2 | 99.60% | SHMT-IN-2 is a stereo specific inhibitor of human SHMT1/2 with IC50 values of 13 nM and 66 nM for SHMT1 and SHMT2, respectively. SHMT-IN-2 can block the growth of many human cancer cells, and has sensitivity for B-cell lymphomas. | ||||||||||||||||||||
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References
Keywords
