2107273-40-3
Chemical Structure
N-(m-PEG4)-N'-(azide-PEG4)-Cy7
- CAS No.: 2107273-40-3
- Formula:C46H66ClN5O8
- Molecular Weight:852.50
IUPAC Name: 2-((1E,3E,5E)-7-((E)-1-(14-azido-3,6,9,12-tetraoxatetradecyl)-3,3-dimethylindolin-2-ylidene)hepta-1,3,5-trien-1-yl)-3,3-dimethyl-1-(2,5,8,11-tetraoxatridecan-13-yl)-3H-indol-1-ium chloride
InChIKey: ISHBUBOOHQEWKB-UHFFFAOYSA-M
SMILES: COCCOCCOCCOCC[N+]1=C(/C=C/C=C/C=C/C=C2N(CCOCCOCCOCCOCCN=[N+]=[N-])C3=C(C=CC=C3)C/2(C)C)C(C)(C)C4=C1C=CC=C4.[Cl-]
Biological Activity: N-(m-PEG4)-N'-(azide-PEG4)-Cy7 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. N-(m-PEG4)-N'-(azide-PEG4)-Cy7 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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N-(m-PEG4)-N'-(azide-PEG4)-Cy7 | N-(m-PEG4)-N'-(azide-PEG4)-Cy7 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. N-(m-PEG4)-N'-(azide-PEG4)-Cy7 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. | |||||||||||||||||||||
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