2127150-20-1
Chemical Structure
Janelia Fluor® 669, SE
Synonym(s): JF669, SE; JF669, NHS
- CAS No.: 2127150-20-1
- Formula:C34H30F3N3O6SSi
- Molecular Weight:693.76
IUPAC Name: 2-(3-(azetidin-1-ium-1-ylidene)-7-(azetidin-1-yl)-5,5-dimethyl-3,5-dihydrodibenzo[b,e]silin-10-yl)-4-((2-((2,5-dioxopyrrolidin-1-yl)oxy)-2-oxoethyl)thio)-3,5,6-trifluorobenzoate
InChIKey: QFHKALIQFJQJKE-UHFFFAOYSA-N
SMILES: C[Si](C)(C1=C/2)C3=CC(N4CCC4)=CC=C3C(C5=C(C(SCC(ON6C(CCC6=O)=O)=O)=C(C(F)=C5C([O-])=O)F)F)=C1C=CC2=[N+]7CCC/7
Biological Activity: Janelia Fluor 669, SE (JF669, SE), a red fluorescent dye, can be directly reacted with the available thiol-containing HaloTag ligand under mild conditions (DIEA, DMF) to afford a JF669HaloTag ligand in a single step (Ex = 669 nm; Em = 682 nm)[1]. Janelia Fluor products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.
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Janelia Fluor® 669, SE | Janelia Fluor 669, SE (JF669, SE), a red fluorescent dye, can be directly reacted with the available thiol-containing HaloTag ligand under mild conditions (DIEA, DMF) to afford a JF669HaloTag ligand in a single step (Ex = 669 nm; Em = 682 nm). Janelia Fluor products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute. | |||||||||||||||||||||
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Keywords