2137977-29-6
2137977-29-6
Chemical Structure
MKP10241
- CAS No.: 2137977-29-6
- Formula:C24H27FN6O3S2
- Molecular Weight:530.64
InChIKey: UUMBXZTUKTTYMG-HNNXBMFYSA-N
SMILES: C[C@@H](C1CCN(CC1)C2=NC=C(C=N2)CC)OC(S3)=NN4C3=NC(C5=CC=C(C=C5F)S(C)(=O)=O)=C4
Biological Activity: MKP10241 is an orally active GPR119 agonist. MKP10241 elevates cAMP levels in the GPR119 expressing cell line (EC50: 3.7 nM). MKP10241 reduces blood glucose levels and HbA1c in acute models and a chronic diabetic mouse model. MKP10241 also demonstrates excellent preclinical efficacy in acute as well as chronic rodent models of obesity, and MASH[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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MKP10241 | 98.06% | MKP10241 is an orally active GPR119 agonist. MKP10241 elevates cAMP levels in the GPR119 expressing cell line (EC50: 3.7 nM). MKP10241 reduces blood glucose levels and HbA1c in acute models and a chronic diabetic mouse model. MKP10241 also demonstrates excellent preclinical efficacy in acute as well as chronic rodent models of obesity, and MASH. | ||||||||||||||||||||
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References
Keywords
