2138439-53-7
2138439-53-7
Chemical Structure
(S,R,S)-AHPC-C4-NH2
Synonym(s): VH032-C4-NH2
- CAS No.: 2138439-53-7
- Formula:C27H39N5O4S
- Molecular Weight:529.69
IUPAC Name: (2S,4R)-1-((S)-2-(5-aminopentanamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide
InChIKey: BJFSHNWASBGXMS-ZFGGDYGUSA-N
SMILES: O=C(NCC1=CC=C(C2=C(C)N=CS2)C=C1)[C@H]3N(C([C@H](C(C)(C)C)NC(CCCCN)=O)=O)C[C@H](O)C3
Biological Activity: (S,R,S)-AHPC-C4-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and a linker used for EED-Targeted PROTAC[1].
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(S,R,S)-AHPC-C4-NH2 | (S,R,S)-AHPC-C4-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and a linker used for EED-Targeted PROTAC. | |||||||||||||||||||||
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References
Keywords
