214140-47-3
Chemical Structure
HMR-3339
- CAS No.: 214140-47-3
- Formula:C30H40ClNO3
- Molecular Weight:498.10
IUPAC Name: (8S,9R,11S,13S,14S,17S)-4-chloro-11-(4-(2-(diethylamino)ethoxy)phenyl)-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthrene-3,17-diol
InChIKey: JNKQAHJZAUFSLB-BAWYVGMJSA-N
SMILES: C[C@@]12[C@](CC[C@@H]2O)([H])[C@@]3([H])[C@](C4=CC=C(O)C(Cl)=C4CC3)([H])[C@@H](C5=CC=C(OCCN(CC)CC)C=C5)C1
Biological Activity: HMR-3339 is a new selective estrogen receptor modulator. HMR-3339 reduces total cholesterol, low-density lipoprotein cholesterol, and homocysteine. HMR-3339 corrects bone alterations induced by ovariectomy[1][2].
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HMR-3339 | HMR-3339 is a new selective estrogen receptor modulator. HMR-3339 reduces total cholesterol, low-density lipoprotein cholesterol, and homocysteine. HMR-3339 corrects bone alterations induced by ovariectomy. | |||||||||||||||||||||
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- [1]. Ammann P, et al. A new selective estrogen receptor modulator HMR-3339 fully corrects bone alterations induced by ovariectomy in adult rats. Bone. 2004 Jul;35(1):153-61. [Content Brief]
- [2]. Vogelvang TE, et al. HMR 3339, a novel selective estrogen receptor modulator, reduces total cholesterol, low-density lipoprotein cholesterol, and homocysteine in healthy postmenopausal women. Fertil Steril. 2004 Dec;82(6):1540-9. [Content Brief]
Keywords
