2159138-01-7
Chemical Structure
PD-1/PD-L1-IN-20
- CAS No.: 2159138-01-7
- Formula:C30H26BrClN2O3
- Molecular Weight:577.90
IUPAC Name: 3-((5-((2-bromo-[1,1'-biphenyl]-3-yl)methoxy)-4-chloro-2-(((2-hydroxyethyl)amino)methyl)phenoxy)methyl)benzonitrile
InChIKey: WFKSDDBJJFYOET-UHFFFAOYSA-N
SMILES: N#CC1=CC=CC(COC2=CC(OCC3=CC=CC(C4=CC=CC=C4)=C3Br)=C(C=C2CNCCO)Cl)=C1
Biological Activity: PD-1/PD-L1-IN-20 (Example 21) is a small-molecule inhibitor of the PD-1/PD-L1 protein-protein interaction. PD-1/PD-L1-IN-20 blocks PD-1/PD-L1 with the IC50 of 5.29 nM. PD-1/PD-L1-IN-20 can be used for the research of cancers, infectious diseases and autoimmune diseases[1].
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PD-1/PD-L1-IN-20 | PD-1/PD-L1-IN-20 (Example 21) is a small-molecule inhibitor of the PD-1/PD-L1 protein-protein interaction. PD-1/PD-L1-IN-20 blocks PD-1/PD-L1 with the IC50 of 5.29 nM. PD-1/PD-L1-IN-20 can be used for the research of cancers, infectious diseases and autoimmune diseases. | |||||||||||||||||||||
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Keywords
