216691-95-1
216691-95-1
Chemical Structure
Bz 423
Synonym(s): BZ48
- CAS No.: 216691-95-1
- Formula:C27H21ClN2O2
- Molecular Weight:440.92
IUPAC Name: 7-chloro-5-(4-hydroxyphenyl)-1-methyl-3-(naphthalen-2-ylmethyl)-1,3-dihydro-2H-benzo[e][1,4]diazepin-2-one
InChIKey: HIJCSNHREFFOML-UHFFFAOYSA-N
SMILES: O=C1N(C)C2=CC=C(Cl)C=C2C(C3=CC=C(O)C=C3)=NC1CC4=CC=C5C=CC=CC5=C4
Biological Activity: Bz 423 is a pro-apoptotic 1,4-benzodiazepine with therapeutic properties in murine models of lupus demonstrating selectivity for autoreactive lymphocytes, and activates Bax and Bak.
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Bz 423 | 99.72% | Bz 423 is a pro-apoptotic 1,4-benzodiazepine with therapeutic properties in murine models of lupus demonstrating selectivity for autoreactive lymphocytes, and activates Bax and Bak. | ||||||||||||||||||||
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Keywords
