216699-33-1
216699-33-1
Chemical Structure
Calcium Green-5N AM
- CAS No.: 216699-33-1
- Formula:C59H52Cl2N4O282-
- Molecular Weight:1335.96
InChIKey: GLNFCJYSPXRWFD-UHFFFAOYSA-N
SMILES: O=C1OC2(C3=CC(Cl)=C(C=C3OC4=CC(OC(C)=O)=C(C=C42)Cl)OC(C)=O)C5=CC=C(C(NC6=CC=C(N(CC(OCOC(C)=O)=O)CC(OCOC(C)=O)=O)C(OCCOC7=CC([N-]([O-])=O)=CC=C7N(CC(OCOC(C)=O)=O)CC(OCOC(C)=O)=O)=C6)=O)C=C15
Biological Activity: Calcium Green-5N AM is a Ca2+-sensitive fluorescent probe (Kd = 14 μM). Calcium Green-5N AM shows enhanced fluorescence intensity upon binding to Ca2+, and it can monitor free Ca2+ in neurons[1][2][3].
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Calcium Green-5N AM | Calcium Green-5N AM is a Ca2+-sensitive fluorescent probe (Kd = 14 μM). Calcium Green-5N AM shows enhanced fluorescence intensity upon binding to Ca2+, and it can monitor free Ca2+ in neurons. | |||||||||||||||||||||
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References
- [1]. Herrick SB, et al. The acrosomal vesicle of mouse sperm is a calcium store. J Cell Physiol. 2005;202(3):663-671. [Content Brief]
- [2]. Thomas D, et al. A comparison of fluorescent Ca2+ indicator properties and their use in measuring elementary and global Ca2+ signals. Cell Calcium. 2000;28(4):213-223. [Content Brief]
- [3]. Rajdev S, et al. Calcium green-5N, a novel fluorescent probe for monitoring high intracellular free Ca2+ concentrations associated with glutamate excitotoxicity in cultured rat brain neurons. Neurosci Lett. 1993;162(1-2):149-152. [Content Brief]
