2170477-75-3
Chemical Structure
RORγt inverse agonist 13
- CAS No.: 2170477-75-3
- Formula:C23H17Cl2F3N2O4
- Molecular Weight:513.29
IUPAC Name: 2-(4-((3-(2,6-dichloro-2'-(trifluoromethoxy)-[1,1'-biphenyl]-4-yl)ureido)methyl)phenyl)acetic acid
InChIKey: ZBAVYJYWRYFFEJ-UHFFFAOYSA-N
SMILES: O=C(O)CC1=CC=C(CNC(NC2=CC(Cl)=C(C3=CC=CC=C3OC(F)(F)F)C(Cl)=C2)=O)C=C1
Biological Activity: RORγt inverse agonist 13 (Compound 3i) is a potent, orally active and selective RORγt inverse agonist, with improved agent-like properties, with an IC50 of 63.8 nM[1].
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RORγt inverse agonist 13 | 98.13% | RORγt inverse agonist 13 (Compound 3i) is a potent, orally active and selective RORγt inverse agonist, with improved agent-like properties, with an IC50 of 63.8 nM. | ||||||||||||||||||||
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Keywords