2170606-74-1
Chemical Structure
DB2313
- CAS No.: 2170606-74-1
- Formula:C42H41FN8O2
- Molecular Weight:708.83
IUPAC Name: 2,2'-((((2-fluoro-1,3-phenylene)bis(methylene))bis(oxy))bis(4,1-phenylene))bis(N-isopropyl-1H-benzo[d]imidazole-6-carboximidamide)
InChIKey: NUVPJXUYFGWDGB-UHFFFAOYSA-N
SMILES: FC1=C(COC2=CC=C(C3=NC4=CC=C(C(NC(C)C)=N)C=C4N3)C=C2)C=CC=C1COC5=CC=C(C6=NC7=CC=C(C(NC(C)C)=N)C=C7N6)C=C5
Biological Activity: DB2313 is a potent inhibitor of transcription factor PU.1. DB2313 inhibits PU.1-dependent reporter gene transactivation with an IC50 of 5 μM. DB2313 disrupts the interaction of PU.1 with target gene promoters. DB2313 induces apoptosis in acute myeloid leukemia (AML) cells and has anticancer effects[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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DB2313 | 99.48% | DB2313 is a potent inhibitor of transcription factor PU.1. DB2313 inhibits PU.1-dependent reporter gene transactivation with an IC50 of 5 μM. DB2313 disrupts the interaction of PU.1 with target gene promoters. DB2313 induces apoptosis in acute myeloid leukemia (AML) cells and has anticancer effects. | ||||||||||||||||||||
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Keywords
