2180914-37-6
2180914-37-6
Chemical Structure
VU6005806
Synonym(s): AZN-00016130
- CAS. Nr.: 2180914-37-6
- Formula:C17H16F3N7O2S
- Molecular Weight:439.41
IUPAC Name: 5-amino-3-methoxy-4-methyl-N-(1-(5-(trifluoromethyl)pyrimidin-2-yl)azetidin-3-yl)thieno[2,3-c]pyridazine-6-carboxamide
InChIKey: VILQHBIGBISKQM-UHFFFAOYSA-N
SMILES: NC1=C(C(NC2CN(C3=NC=C(C(F)(F)F)C=N3)C2)=O)SC4=NN=C(OC)C(C)=C41
Biological Activity: VU6005806 (AZN-00016130) is a potent muscarnic acethylcholine receptor subtype 4 (M4) positive allosteric modulator (PAM), with EC50s of 94 nM, 28 nM, 87 nM and 68 nM for human, rat, dog and cyno M4, respectively. Used in the research of neuropsychiatric disorders[1].
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VU6005806 | VU6005806 (AZN-00016130) is a potent muscarnic acethylcholine receptor subtype 4 (M4) positive allosteric modulator (PAM), with EC50s of 94 nM, 28 nM, 87 nM and 68 nM for human, rat, dog and cyno M4, respectively. Used in the research of neuropsychiatric disorders. | |||||||||||||||||||||
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