1. GPCR/G Protein
    Neuronal Signaling
  2. mAChR
  3. VU6005806

VU6005806 (Synonyms: AZN-00016130)

Cat. No.: HY-128584
Handling Instructions

VU6005806 (AZN-00016130) is a potent muscarnic acethylcholine receptor subtype 4 (M4) positive allosteric modulator (PAM), with EC50s of 94 nM, 28 nM, 87 nM and 68 nM for human, rat, dog and cyno M4, respectively. Used in the research of neuropsychiatric disorders.

For research use only. We do not sell to patients.

VU6005806 Chemical Structure

VU6005806 Chemical Structure

CAS No. : 2180914-37-6

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Description

VU6005806 (AZN-00016130) is a potent muscarnic acethylcholine receptor subtype 4 (M4) positive allosteric modulator (PAM), with EC50s of 94 nM, 28 nM, 87 nM and 68 nM for human, rat, dog and cyno M4, respectively. Used in the research of neuropsychiatric disorders[1].

IC50 & Target

IC50: 94 nM (Human M4), 28 nM (Rat M4), 87 nM (Dog M4), 68 nM (Cyno M4)[1]

Molecular Weight

439.41

Formula

C₁₇H₁₆F₃N₇O₂S

CAS No.

2180914-37-6

SMILES

NC1=C(C(NC2CN(C3=NC=C(C(F)(F)F)C=N3)C2)=O)SC4=NN=C(OC)C(C)=C41

Shipping

Room temperature in continental US; may vary elsewhere

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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VU6005806
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