2182653-84-3
2182653-84-3
Chemical Structure
LH1306
- CAS No.: 2182653-84-3
- Formula:C38H48N6O6
- Molecular Weight:684.82
IUPAC Name: N,N'-(((((((2,2'-dimethyl-[1,1'-biphenyl]-3,3'-diyl)bis(methylene))bis(oxy))bis(2-methoxypyridine-6,3-diyl))bis(methylene))bis(azanediyl))bis(ethane-2,1-diyl))diacetamide
InChIKey: ZNRITEYTYHQVTF-UHFFFAOYSA-N
SMILES: CC(NCCNCC(C(OC)=N1)=CC=C1OCC2=CC=CC(C3=CC=CC(COC4=CC=C(C(OC)=N4)CNCCNC(C)=O)=C3C)=C2C)=O
Biological Activity: LH1306 is a C2-symmetric inhibitor of PD-1/PD-L1 protein-protein interaction (PPI), with an IC50 value of 25 nM. LH1306 can be used in anti-tumor research[1].
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LH1306 | LH1306 is a C2-symmetric inhibitor of PD-1/PD-L1 protein-protein interaction (PPI), with an IC50 value of 25 nM. LH1306 can be used in anti-tumor research. | |||||||||||||||||||||
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References
Keywords
