22006-84-4
22006-84-4
Chemical Structure
Denopterin
Synonym(s): Pteroylglutamic acid
- CAS No.: 22006-84-4
- Formula:C21H23N7O6
- Molecular Weight:469.45
IUPAC Name: (4-((1-(2-amino-4-oxo-4,8-dihydropteridin-6-yl)ethyl)(methyl)amino)benzoyl)-L-glutamic acid
InChIKey: FLWWDYNPWOSLEO-HQVZTVAUSA-N
SMILES: O=C1C2=NC(C(C)N(C3=CC=C(C=C3)C(N[C@H](C(O)=O)CCC(O)=O)=O)C)=CNC2=NC(N)=N1
Biological Activity: Denopterin is a dihydrofolate reductase (DHFR) inhibitor and an antifolate agent. Denopterin is an antimetabolite that has toxic effects on cells and can be used for cancer[1].
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Denopterin | Denopterin is a dihydrofolate reductase (DHFR) inhibitor and an antifolate agent. Denopterin is an antimetabolite that has toxic effects on cells and can be used for cancer. | |||||||||||||||||||||
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