2227434-74-2
2227434-74-2
Chemical Structure
BRP-201
- CAS No.: 2227434-74-2
- Formula:C28H27ClN4OS
- Molecular Weight:503.06
IUPAC Name: 5-(1-(2-chlorobenzyl)-2-(1-(4-isobutylphenyl)ethyl)-1H-benzo[d]imidazol-5-yl)-1,3,4-oxadiazole-2(3H)-thione
InChIKey: ZADYAZTTWZYTSD-UHFFFAOYSA-N
SMILES: S=C1OC(C2=CC=C3C(N=C(C(C4=CC=C(CC(C)C)C=C4)C)N3CC5=CC=CC=C5Cl)=C2)=NN1
Biological Activity: Brp-201 is considered as a promising therapeutic target for the next generation of anti-inflammatory drugs in the research of inflammatory diseases. It is a new, effective and selective inhibitor of mPGES-1 with an IC50 value of 0.42 μM.
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BRP-201 | Brp-201 is considered as a promising therapeutic target for the next generation of anti-inflammatory drugs in the research of inflammatory diseases. It is a new, effective and selective inhibitor of mPGES-1 with an IC50 value of 0.42 μM. | |||||||||||||||||||||
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Keywords
