2230821-40-4

SJF-1521 Chemical Structure
2230821-40-4

Chemical Structure

SJF-1521

  • CAS No.: 2230821-40-4
  • Formula:C57H61ClFN7O9S
  • Molecular Weight:1074.65

IUPAC Name: (2S,4R)-1-((S)-2-(tert-butyl)-14-(4-(4-((3-chloro-4-((3-fluorobenzyl)oxy)phenyl)amino)quinazolin-6-yl)phenoxy)-4-oxo-6,9,12-trioxa-3-azatetradecanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide

InChIKey: XZNORRXEBCTXPB-KHBXAZQSSA-N

SMILES: O=C(N1[C@@H](C[C@H](C1)O)C(NCC2=CC=C(C3=C(N=CS3)C)C=C2)=O)[C@H](C(C)(C)C)NC(COCCOCCOCCOC(C=C4)=CC=C4C5=CC(C(NC6=CC(Cl)=C(C=C6)OCC7=CC(F)=CC=C7)=NC=N8)=C8C=C5)=O

Biological Activity: SJF-1521 is a selective EGFR PROTAC degrader. SJF-1521 is capable of inducing EGFR degradation in OVCAR8 cells. SJF-1521 can be used for tumor research[1].

Cat. No. Product Name Purity Description Pricing
HY-131865
SJF-1521 99.65% SJF-1521 is a selective EGFR PROTAC degrader. SJF-1521 is capable of inducing EGFR degradation in OVCAR8 cells. SJF-1521 can be used for tumor research.
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