2237222-16-9
2237222-16-9
Chemical Structure
PSB-CB-27
- CAS No.: 2237222-16-9
- Formula:C25H27ClN2O3S
- Molecular Weight:471.01
InChIKey: GUVYPTUVBVOIOM-NKFKGCMQSA-N
SMILES: O=C1N2C(SCCC2)=N/C1=C\C3=CC(OCCCCCCOC4=CC=C(C=C4)Cl)=CC=C3
Biological Activity: PSB-CB-27 is a potent and selective GPR18 inhibitor with an IC50 of 0.65 μM. PSB-CB-27 shows selectivity over Human GPR55, Human CB1 receptor, and Human CB2 receptor. PSB-CB-27 leads to a complete blockade of Δ9-Tetrahydrocannabinol (THC)-induced GPR18 activation. PSB-CB-27 can be used for inflammatory diseases and cancer immunotherapy research[1].
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PSB-CB-27 | PSB-CB-27 is a potent and selective GPR18 inhibitor with an IC50 of 0.65 μM. PSB-CB-27 shows selectivity over Human GPR55, Human CB1 receptor, and Human CB2 receptor. PSB-CB-27 leads to a complete blockade of Δ9-Tetrahydrocannabinol (THC)-induced GPR18 activation. PSB-CB-27 can be used for inflammatory diseases and cancer immunotherapy research. | |||||||||||||||||||||
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References
Keywords
