2241315-66-0
2241315-66-0
Chemical Structure
BWA-522 intermediate-1
- CAS No.: 2241315-66-0
- Formula:C19H19N3O5
- Molecular Weight:369.37
InChIKey: TXZFWPHJZKOMQY-UHFFFAOYSA-N
SMILES: O=CC1CCN(C2=CC3=C(C(N(C(CC4)C(NC4=O)=O)C3=O)=O)C=C2)CC1
Biological Activity: BWA-522 intermediate-1 is an intermediate in the synthesis of PROTAC BWA-522 (HY-149433) and serves as a ligand molecule for cereblon E3 ubiquitin ligase. BWA-522 is an orally active small molecule protein-targeting chimera (PROTAC) that has significant degradation effects on AR-FL and AR-V7[1].
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BWA-522 intermediate-1 | 99.27% | BWA-522 intermediate-1 is an intermediate in the synthesis of PROTAC BWA-522 (HY-149433) and serves as a ligand molecule for cereblon E3 ubiquitin ligase. BWA-522 is an orally active small molecule protein-targeting chimera (PROTAC) that has significant degradation effects on AR-FL and AR-V7. | ||||||||||||||||||||
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References
Keywords
