2247314-23-2
2247314-23-2
Chemical Structure
SGLT inhibitor-1
- CAS No.: 2247314-23-2
- Formula:C24H27FO8
- Molecular Weight:462.46
IUPAC Name: (2S,3R,4R,5S,6R)-2-(7-((2,3-dihydrobenzo[b][1,4]dioxin-6-yl)methyl)-4-methoxy-2,3-dihydrobenzofuran-5-yl)-5-fluoro-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4-diol
InChIKey: QUHJWCHBJBZVQP-IDYLKPADSA-N
SMILES: OC[C@@H]1[C@@H](F)[C@H](O)[C@@H](O)[C@H](C2=CC(CC3=CC(OCCO4)=C4C=C3)=C(OCC5)C5=C2OC)O1
Biological Activity: SGLT inhibitor-1 is a potent dual inhibitor of sodium glucose co-transporter proteins (SGLTs), inhibits hSGLT1 and hSGLT2 with IC50s of 43 nM and 9 nM, respectively[1].
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SGLT inhibitor-1 | SGLT inhibitor-1 is a potent dual inhibitor of sodium glucose co-transporter proteins (SGLTs), inhibits hSGLT1 and hSGLT2 with IC50s of 43 nM and 9 nM, respectively. | |||||||||||||||||||||
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References
Keywords
