2247881-73-6
2247881-73-6
Chemical Structure
AQIM-I
- CAS No.: 2247881-73-6
- Formula:C17H13IN2O2
- Molecular Weight:404.20
InChIKey: LBSPLTAVJDMKOH-UHFFFAOYSA-M
SMILES: O=C1C2=C(C(C3=CC4=C(C=C31)C=CC=C4)=O)N(C=[N+]2C)C.[I-]
Biological Activity: AQIM-I is an inhibitor of survivin via inhibits survivin expression and colony formation. AQIM-I induces ROS production, apoptosis, cell cycle arrest, DNA damage, and autophagy. AQIM-I inhibits nonsmall cell lung cancer cells A549 with an IC50 value of 9 nM[1].
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AQIM-I | AQIM-I is an inhibitor of survivin via inhibits survivin expression and colony formation. AQIM-I induces ROS production, apoptosis, cell cycle arrest, DNA damage, and autophagy. AQIM-I inhibits nonsmall cell lung cancer cells A549 with an IC50 value of 9 nM. | |||||||||||||||||||||
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References
Keywords
